For which of the following conditions is etomidate contraindicated?

Etomidate is a non-barbiturate sedative-hypnotic agent that is commonly used for rapid sequence intubation due to its favorable side effect profile. It is known for its minimal cardiovascular effects, making it a preferred choice in patients who are hemodynamically unstable or in shock. However, etomidate is contraindicated in certain scenarios.

In the context of shock patients, the primary concern is etomidate's adrenal suppressive effects. Etomidate can inhibit cortisol synthesis, which may be particularly detrimental in patients experiencing septic shock or other forms of shock where adequate adrenal response is critical for survival and managing the stress response effectively. Administering etomidate to a patient who is already in shock could exacerbate their condition by reducing their ability to mount an appropriate physiological response.

For the other conditions listed, although there are other medications that may be preferred for patients with anxiety, diabetes, or hypertension, etomidate itself does not pose a direct contraindication in these scenarios. It is crucial to assess each patient individually and consider their overall clinical picture, but the specific adrenal considerations in shock patients distinctly underscore why etomidate is contraindicated in that context.