In addition to adrenal suppression and hemodynamic instability, which situation requires caution when administering etomidate?

Caution must be taken when administering etomidate to patients with chronic obstructive pulmonary disease (COPD) or asthma due to the potential for respiratory depression. Etomidate is known for its minimal cardiovascular effects and rapid onset, making it a popular choice for rapid sequence intubation. However, in patients with compromised respiratory function, such as those with COPD or asthma, even minimal respiratory effects can worsen their already fragile state.

These patients may require careful monitoring of their respiratory status and additional measures to ensure that they can maintain adequate ventilation. The quick onset of etomidate can potentially lead to respiratory compromise, especially if there’s an underlying issue with pulmonary function. Thus, it is essential to be aware of their specific respiratory conditions and to prepare for any additional support they may need following administration of the medication.