What are the symptoms associated with Transfusion Related Acute Lung Injury (TRALI)?

Transfusion Related Acute Lung Injury (TRALI) is a serious complication that can occur after blood transfusions. The symptoms of TRALI typically manifest quickly after the transfusion and often resemble other pulmonary issues, making it critical to recognize them for timely management.

The correct answer includes dyspnea (shortness of breath), tachycardia (increased heart rate), fever, and cyanosis (bluish discoloration of the skin due to lack of oxygen). Dyspnea is a hallmark sign of lung injury, indicating respiratory distress, and tachycardia can occur as the body attempts to compensate for decreased oxygenation. Fever is also common in inflammatory responses, and cyanosis indicates severe hypoxemia or insufficient oxygen in the blood.

Recognizing these specific symptoms is vital for healthcare professionals to differentiate TRALI from other transfusion reactions or respiratory issues and to initiate appropriate interventions, such as providing supplemental oxygen or supportive care immediately. This understanding is critical in emergency and critical care settings where blood transfusions are a common intervention.