What is a significant concern for a patient with SIADH?

In the context of Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH), a significant concern for patients is hyponatremia, which is a low sodium concentration in the blood. SIADH is characterized by excessive release of antidiuretic hormone (ADH), leading to water retention and dilution of serum sodium levels.

Patients with SIADH retain more water than normal, which decreases serum sodium levels. This dilutional hyponatremia can lead to various neurological symptoms due to swelling of brain cells; symptoms may include confusion, seizures, and in severe cases, coma. Therefore, monitoring sodium levels and managing hyponatremia is crucial in the treatment of patients with SIADH to prevent further complications.

The other options, while they may be significant in different contexts, do not directly relate to the primary concerns associated with SIADH.