What is the duration of Propofol (Diprivan)?

Propofol, commonly known as Diprivan, is a fast-acting sedative agent used for induction and maintenance of anesthesia. The onset of action is rapid, usually within about 30 seconds, and its duration of effect is relatively short. The effects of a single bolus dose typically last about 5 to 10 minutes, which corresponds with the correct answer in this instance.

This brief duration is primarily due to the drug's pharmacokinetics; it is quickly distributed in the body and metabolized by the liver, resulting in a rapid recovery phase. Consequently, patients often regain consciousness quickly after the administration of Propofol, making it a preferred choice for procedures requiring sedation where quick recovery is desirable.

Understanding the duration of Propofol is crucial for providers in critical care settings to ensure appropriate monitoring and management of sedation in patients.