What is the maintenance infusion rate of insulin for hyperglycemia treatment?

The maintenance infusion rate of insulin for the treatment of hyperglycemia is typically set at 0.1 unit/kg/hr. This rate is based on clinical guidelines and the pharmacokinetics of insulin, which allow for effective management of blood glucose levels without the risk of inducing hypoglycemia.

Using this infusion rate helps to achieve a steady-state concentration of insulin, allowing for precise control over blood sugar levels in critically ill patients or those requiring intensive monitoring. This rate supports the physiological needs for glycemic control, as it promotes gradual adjustments to blood glucose without overwhelming the body's ability to respond.

The choice of a 0.1 unit/kg/hr infusion rate also reflects the need to balance efficacy with safety, minimizing the risk of drastic fluctuations that can complicate a patient's clinical condition. In cases of severe hyperglycemia or diabetic ketoacidosis, this calculated approach to insulin infusion is particularly important in managing the patient's metabolic state effectively.