What is the maximum duration for a continuous ketamine infusion during post-intubation?

The maximum duration for a continuous ketamine infusion during post-intubation is considered to be up to 2 hours. Ketamine is a versatile anesthetic that not only provides sedation but also analgesia, making it useful in critically ill patients requiring intubation and subsequent management.

When used in a continuous infusion, particularly post-intubation, ketamine can help maintain sedation without the risks associated with repeated boluses. However, it is essential to monitor the patient for hemodynamic stability and signs of respiratory depression during its use.

The 2-hour limit is generally based on clinical guidelines intended to minimize potential side effects, such as dissociative effects and prolonged sedation. This timeframe ensures that healthcare providers can reassess the patient's sedation needs and the overall clinical picture. After 2 hours, many protocols recommend evaluating the patient's response and potentially adjusting the sedative regimen based on their needs and any developing clinical situations.