What is the maximum rate of lowering blood pressure during a hypertensive crisis?

In a hypertensive crisis, it is crucial to lower the blood pressure in a controlled and gradual manner to prevent complications such as organ ischemia or neurological events. The standard recommendation is to reduce the mean arterial pressure by no more than 25% within the first hour of treatment. This ensures that the body can accommodate the changes and helps to avoid potential adverse effects associated with a rapid decrease in blood pressure.

The goal is to achieve a safer blood pressure level without precipitating ischemic damage to vital organs. As a result, the approach is to closely monitor the patient while therapeutically managing their blood pressure to achieve this gradual reduction.

In this context, achieving a reduction of approximately 25% within the first hour is considered optimal and aligns with established medical guidelines.