What is the normal osmolality range for human plasma?

The normal osmolality range for human plasma is critical for understanding fluid balance and assessing various medical conditions. It is measured in milliosmoles per kilogram (mOsm/kg) and reflects the concentration of solutes in the blood. The typical range of 275-295 mOsm/kg signifies the balance of electrolytes, proteins, and other solutes that are key to maintaining physiological homeostasis.

Values outside of this range can indicate different pathological states. For instance, lower osmolality levels might suggest conditions such as hyponatremia, while higher levels could indicate dehydration or hypernatremia. Understanding this range is essential for critical care paramedics, who often assess patients for signs of fluid overload or deficit, electrolyte imbalances, or other significant health issues.