What is the recommended maintenance dose for Vecuronium (Norcuron) in adults?

The recommended maintenance dose for Vecuronium (Norcuron) in adults is typically in the range of 0.01 to 0.1 mg/kg. This dosage is aimed at ensuring effective neuromuscular blockade while minimizing the potential for side effects or prolonged paralysis that can result from higher doses.

Vecuronium is a non-steroidal muscle relaxant used in critical care settings for intubation and to facilitate mechanical ventilation. The lower dosing range is preferred in the maintenance phase because it effectively maintains neuromuscular blockade without putting patients at greater risk for complications such as respiratory depression or prolonged recovery time.

The choice of the maintenance dose can also depend on various factors, including the patient’s response to the initial bolus, their overall health, and any concurrent medications that might influence neuromuscular transmission. Adjustments might be necessary based on continuous monitoring, but within the established range of 0.01 to 0.1 mg/kg, most patients can achieve optimal results after the initial phase of administration.