Which syndrome presents with more significant upper extremity loss than lower extremity?

Central Cord Syndrome is characterized by a greater loss of function in the upper extremities compared to the lower extremities. This condition often occurs due to damage to the central part of the spinal cord, typically from trauma or degenerative conditions. The anatomical layout of the spinal cord dictates that upper extremity motor fibers are located more centrally, which is why injuries affecting this area lead to the hallmark clinical presentation of weakness or paralysis predominantly in the arms while the legs may still retain normal function or be less affected.

Understanding the syndrome helps clarify its implications for treatment and rehabilitation. Patients may experience varying degrees of sensory and motor deficits, but the hallmark is the disproportionate impact on the upper limbs, which often necessitates focused therapeutic strategies to enhance upper extremity function. The other conditions mentioned affect motor control and sensory pathways differently but typically do not present with the same specific pattern of disproportionate upper limb involvement.